opportunity
be part of reshaping the
druggable space
Proxygen uses the most cutting-edge technologies to identify and develop molecular glue degraders. For the first time, we have the tools to create tangible improvements in the treatment of previously untreatable diseases.
team
interdisciplinary approach
for a joint goal
Proxygen brings together scientists from a variety of fields, ranging from chemistry to molecular biology and data science, who share the same goal: to reshape the boundaries of drug development by exploiting the enormous potential of molecular glue degraders.
career
flexibility
the best of two worlds
At Proxygen, we adapt each role to the employee’s needs and interests. We adhere to the academic spirit of giving everyone the freedom to develop in their own direction. We support our employees in improving their skills and expertise while providing them with the opportunity to take on more responsibilities when desired.
VBC – vienna
bio center
a leading european science hub
Proxygen is located at the Vienna BioCenter, one of Europe’s largest life science hubs. This inter-disciplinary and inter-sectoral campus offers a unique combination of research, education, and biotechnology. Its rapidly growing startup and corporate scene is currently home to 33 companies.
vienna
the most liveable city
The Austrian capital has topped “the world’s highest quality of living” rankings for the past ten years and was crowned “the world’s greenest city” in 2020. Features that make Vienna such an attractive city include:
Affordable high-quality
housing & reliable &
affordable public transport
An international airport with
non-stop flights to all
major cities in Europe
First-class public
healthcare &
public education
Parks, recreational
areas & other green
spaces making up
50% of the urban area
A large variety of cultural
facilities & leisure
activities inside &
outside the city
A young, international
population & very high
penetrance of english as a
second language
open positions
research technician (f/m/d)
10.05.21
10.05.21
research technician (f/m/d)
Proxygen harnesses the cellular protein quality control system to develop therapies against cancer and other life-threatening diseases. We are focused on particular small molecules called “molecular glue degraders” which mediate recruitment of a disease-causing protein to a ubiquitin ligase where it is ubiquitinated and directed to the proteasome for degradation. Hence, instead of merely blocking the function of harmful proteins, molecular glue degraders enable their complete and selective elimination.
Proxygen is located in the VBC6 Startup Labs, a new co-working space for biotech companies embedded in the Vienna Biocenter campus, one of Europe’s hotspots for life sciences. Within this context, Proxygen creates a vibrant, dynamic, and inclusive work environment with a strong emphasis on collaboration and teamwork.
We are looking for an enthusiastic full-time research technician (f/m/d) excited to join our team.
who we are looking for
- Bachelor’s or master’s degree in the life sciences – candidates with a TA diploma (HTL) will also be considered
- Previous wet-lab experience, in particular familiarity with culturing and genetic engineering of mammalian cell lines, is an advantage
- Experience with chemical or genetic screening is considered a plus
- Proficiency with MS Office and willingness to learn new software applications
- Good written and oral communication skills in English are required
- Excellent organizational skills and attention for detail
- High accuracy, reliability and excellent interpersonal and organizational skills
- Positive attitude, reliability, professionalism, and team player mentality
what your main responsibilities will be
- Handling and manipulation of mammalian cell lines (thaw, freeze and culture cells, genome engineering, cellular assays)
- Planning, execution, and analysis of experiments with focus on molecular biology (e.g. PCR, cloning) and biochemistry methods (e.g. Western blot)
- Sample preparation for large-scale proteomic and genomic experiments
- Assay development and establishment of SOP’s
- Accurate and meticulous recording of work processes and results according to internal documentation practices
what we offer
- International & multidisciplinary team of scientists consisting of molecular biologists, computational biologists and chemists
- Participation in cutting edge research with the overall goal to improve therapeutic options for cancer patients
- Opportunity to contribute to one of the hottest fields in drug discovery
- Support of professional development according to individual goals and aspirations
- Competitive salary based on the applicant’s skills and experience
- Access to state-of-the-art infrastructure
about vienna
The Austrian capital has come out on top of “the world’s highest quality of living” rankings for the past ten years and recently won “the world’s greenest city” award in 2020.
Reasons for Vienna’s prime positioning include:
- Affordable high-quality housing, reliable and affordable public transport
- International airport with non-stop flights to all major cities in Europe
- First-class public healthcare and public educational system
- Parks, recreational areas and other green spaces constituting 50% of the urban area
- Large variety of cultural facilities and leisure activities inside and outside the city
- Young, international population & very high penetrance of english as a second language
We are legally obliged by Austrian law to state a minimum base salary according to the collective agreement for this full-time position (€1957,64 per month, payed out 14 times a year). Salary and conditions will however be commensurate to the experience of the candidate and can be negotiated.
application details
Please submit your comprehensive application, including a detailed letter of motivation and curriculum vitae with contact details of two referees to hr@proxygen.com as a single PDF. Applications will be reviewed on a rolling basis until the position is filled.
senior research scientist (f/m/d)
10.05.21
10.05.21
senior research scientist (f/m/d)
Proxygen harnesses the cellular protein quality control system to develop therapies against cancer and other life-threatening diseases. We are focused on particular small molecules called “molecular glue degraders” which mediate recruitment of a disease-causing protein to a ubiquitin ligase where it is ubiquitinated and directed to the proteasome for degradation. Hence, instead of merely blocking the function of harmful proteins, molecular glue degraders enable their complete and selective elimination.
Proxygen is located in the VBC6 Startup Labs, a new co-working space for biotech companies embedded in the Vienna Biocenter campus, one of Europe’s hotspots for life sciences. Within this context, Proxygen creates a vibrant, dynamic, and inclusive work environment with a strong emphasis on collaboration and teamwork.
We are looking for an enthusiastic full-time senior research scientist (f/m/d) excited to join our team.
who we are looking for
- Postdoctoral researcher with a focus on biochemistry, molecular or cell biology
- Solution-oriented, persistent individual with an independent, well-structured and goal-oriented working style
- Proven scientific track record that includes at least one first author publication in one of the aforementioned fields
- Experience in supervision and management of small teams is preferred
- Prior work experience in industry or Biotech is of advantage
- Experience in (high-content) microscopy, functional genomics (including CRISPR/Cas9 screens), chemical screening or proteomics will be considered an advantage
- Familiarity with cancer research or the biology of the ubiquitin-proteasome system is desirable
- Experience in genetic engineering of mammalian cell lines using CRISPR/Cas9 and reporter assay development is preferred
- Fluency in Python and/or R is a plus
- Good written and oral communication skills in English are required
- Excellent organizational skills and attention for detail
- High accuracy, reliability and excellent interpersonal and organizational skills
- Positive attitude, reliability, professionalism, and team player mentality
what your main responsibilities will be
- Implementation, execution and analysis of phenotypic drug screens
- Drug target identification via a combination of (chemical) proteomics and functional genomics, assay development and standardization
- Accurate and meticulous recording of work processes and results according to internal documentation practices
- Leading a team of additional scientists
- Contribution to communication/reporting with external pharma partnerships, internal and external presentations
what we offer
- International & multidisciplinary team of scientists consisting of molecular biologists, computational biologists, and chemists
- Participation in cutting edge research with the overall goal to improve therapeutic options for cancer patients
- Opportunity to contribute to one of the hottest fields in drug discovery
- Support of professional development according to individual goals and aspirations
- Competitive salary based on the applicant’s skills and experience
- Access to state-of-the-art infrastructure
about vienna
The Austrian capital has come out on top of “the world’s highest quality of living” rankings for the past ten years and recently won “the world’s greenest city” award in 2020.
Reasons for Vienna’s prime positioning include:
- Affordable high-quality housing, reliable and affordable public transport
- International airport with non-stop flights to all major cities in Europe
- First-class public healthcare and public educational system
- Parks, recreational areas and other green spaces constituting 50% of the urban area
- Large variety of cultural facilities and leisure activities inside and outside the city
- Young, international population & very high penetrance of english as a second language
Salary and conditions will be commensurate to the experience of the candidate, starting at EUR 53.000 gross per year.
application details
Please submit your comprehensive application, including a detailed letter of motivation and curriculum vitae with contact details of two referees to hr@proxygen.com as a single PDF. Applications will be reviewed on a rolling basis until the position is filled.
If none of the open positions seem to be an obvious fit for you, feel free to drop us a line or two. We are always looking for talented, curious and open-minded individuals!
